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关 键 词：提供GPMAW正版软件
行 业：IT 软件 实用工具软件
发布时间：2021-09-27
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When asking GPMAW to align the sequences, the program will call ClustalW.exe (if located correctly in the \gpmaw\bin\clustalw\ directory) and the alignment will take place in the background (GPMAW will show a counter while waiting). After the alignment ClustalW will save to a file on disk, which will be loaded and arranged by GPMAW. Remember to right-click in the window to view options.
Sequence handling: Import of sequences from a number of different formats with direct database search in Entrez and in local databases (FastA format and Swiss-Prot). Sequences can be saved in local files (databases) for future reference.
From the sequence window a large number of actions can be performed. Sequences can be exported in FastA format (either singly or all sequences at once) for easy transfer to other programs.
Mass analysis: The protein can be cleaved by automatic methods (e.g. a flexible nomenclature for defining enzyme actions) or manually. The peptides are displayed with a number of parameters (various mass values - mono, ave, charges - Bull&Breese index, HPLC index, pI, charge) and can be further worked upon (e.g. cross-linked, new cleavage).
Peptide mass searches can be performed on any local database in FastA format.
Bioinformatics: A number of graphs can be displayed, hydrophobicity, dot-plot, secondary structure prediction. BLAST searches can be performed on local databases. Multiple alignment using ClustalW.
The CustalW executable is now part of the GPMAw package, but on previous versions you have to install yourself. Read here how.
Main toolbar – Seach & cleavage section:
This shows a GPMAW sequence library files containing multiple sequences. As a sequence file is limited to a size of 264000 bytes (characters), there is a limit to the number of sequences that can be stored in a single library. In the present library, ‘blood.seq’, you can see (status bar at the bottom) that the file is 9% filled.
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